The ADAPTE framework is a systematic approach to aid in the adaptation of guidelines produced in one setting to be used in a different cultural and/or organizational context.
The ADAPTE framework is based on the following core principles:

• Respect of evidence-based principles for guideline development;
  
  
• Reliable and consistent methods to ensure the quality of the adapted guideline;
  
  
• Participation of key stakeholders to foster acceptance and ownership of the adapted guideline;
  
  
• Explicit consideration of context to ensure relevance for local practice and policies;
  
  
• Transparent reporting to promote confidence in the recommendations of the adapted guideline;
  
  
• Flexible format to accommodate specific needs and circumstances;
  
  
• Respect for and acknowledgement of source guidelines material.

The ADAPTE framework is supported by training resources, in particular a Manual and a Technical guide which includes tools that describe and facilitate guideline adaptation.

The ADAPTE framework is intended to be used by different groups, i.e. guideline developers, health care providers and policy makers at the local, national and international level.